Symmetric corticobasal degeneration (S-CBD)
نویسندگان
چکیده
منابع مشابه
Corticobasal degeneration.
Corticobasal degeneration is a progressive neurodegenerative disease that typically presents with asymmetrical parkinsonism and cognitive dysfunction. Recent molecular advances have given some clues to the pathogenesis of the disease. Clinical diagnosis is complicated by both the variability of presentation of true corticobasal degeneration, for example as a dementing illness, and the syndromes...
متن کاملCorticobasal degeneration
75 Introduction and history While historical review suggests earlier reports of the entity now known as corticobasal degeneration (CBD), the disease was fi rst clearly described in a series of three cases in 1968, when it was termed corticodentatonigral degeneration with neuronal achromasia [ 1 ]. Subsequent terminology has included corticonigral degeneration with neuronal achromasia [ 2 ], cor...
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Recent clinical experience and advances in molecular biology made this thesis a possibility although not universally acceptable. Stating it another way, such as CBD and PSP are similar and overlap clinically and pathologically would encounter much less opposition. Is this then just the matter of the extent of the overlap? I shall examine the clinical and the biological evidence and demonstrate ...
متن کاملCognitive dysfunction in corticobasal degeneration.
Corticobasal degeneration (CBD) was originally described as a distinct clinicopathological entity in 1967. Since then, different phenotypic presentations have emerged as possible manifestations of CBD histopathological findings. In addition, pathophysiological findings and the molecular basis have been delineated and several aspects of its cognitive manifestations have been clarified. Thus, not...
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INTRODUCTION Corticobasal syndrome (CBS) has a heterogeneous clinical presentation with no specific pathologic substratum. Its accurate diagnosis is a challenge for neurologists; in order to establish CBS definitively, postmortem confirmation is required. Some clinical and radiological features can help to distinguish it from other neurodegenerative conditions, such as Creutzfeldt-Jakob disease...
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ژورنال
عنوان ژورنال: Parkinsonism & Related Disorders
سال: 2010
ISSN: 1353-8020
DOI: 10.1016/j.parkreldis.2009.11.013